5–5])
You may also get a high potassium level (hyperkalemia) from an overdose
Severe hypokalaemia can be managed by intravenous administration of additional potassium
Digoxin exhibits its therapeutic and toxic effects by poisoning the sodium-potassium ATPase
Mechanism of Action: Inhibits Na/K ATPase, an enzyme that regulates the quantity of sodium and potassium inside cells Use in Patients with Electrolyte Disorders: In patients with hypokalemia or hypomagnesemia, toxicity may occur despite serum digoxin concentrations below 2
Digoxin toxicity in patients with normokalemic potassium depletion Reviews of large series of patients with digitalis-induced arrhythmias create a seeming paradox: Hypokalemia is
It occurs when your blood serum level exceeds 5
The inotropic effect increased parallel with the uptake of digoxin; 10 min after digoxin, contractility was 127% of the control value and this increased to 139% at 90 minutes